| FRA32 | LILLE OSC (Lille OSC Métropole) | ||||||||||
| season | cup | round | opponents | result | scorers | result | scorers | ||||
| 01-02 | E1 | P3 | Parma AC | A | 2-0 | Landrin, Ecker | H | 0-1 | |||
| G1 | RC Deportivo La Coruña | H | 1-1 | Olufadé | A | 1-1 | Br.Cheyrou | ||||
| G1 | Manchester United FC | A | 0-1 | H | 1-1 | Br.Cheyrou | |||||
| G1 | PAE Olympiakos SFP Peiraias | H | 3-1 | Bakari, Br.Cheyrou, Tafforeau | A | 1-2 | Bassir | ||||
| E3 | 16 | AC Fiorentina | A | 1-0 | Bakari | H | 2-0 | Br.Cheyrou, Sterjovski | |||
| 08 | BV 09 Borussia Dortmund | H | 1-1 | Bassir | A | 0-0 | + | ||||
| 04-05 | E3 | R1 | Shelbourne FC Dublin | A | 2-2 | Bodmer, Landrin | H | 2-0 | Ačimović, Moussilou | ||
| R2 | TSV Alemannia Aachen | A | 0-1 | ||||||||
| R2 | FK Zenit Sankt-Peterburg | H | 2-1 | Tafforeau, Moussilou | |||||||
| R2 | AEK Athina | A | 2-1 | Vitakić, Debuchy | |||||||
| R2 | Sevilla FC | H | 1-0 | Moussilou | |||||||
| 16 | FC Basel | A | 0-0 | H | 2-0 | Moussilou, Ačimović | |||||
| 08 | AJ Auxerroise | A | 0-1 | H | 0-0 | ||||||
| 05-06 | E1 | G1 | Sport Lisboa e Benfica | A | 0-1 | H | 0-0 | ||||
| G1 | Villarreal CF | H | 0-0 | A | 0-1 | ||||||
| G1 | Manchester United FC | A | 0-0 | H | 1-0 | Ačimović | |||||
| E3 | 16 | FK Shakhtar Donetsk | H | 3-2 | Fauvergue, Dernis, Odemwingie | A | 0-0 | ||||
| 08 | Sevilla FC | H | 1-0 | Dernis | A | 0-2 | |||||
| 06-07 | E1 | P3 | Rabotnički Kometal Skopje | H | 3-0 | Jovanovski (o.g.), Bastos, Fauvergue | A | 1-0 | Audel | ||
| G1 | RSC Anderlecht (Bruxelles) | A | 1-1 | Fauvergue | H | 2-2 | Odemwingie, Fauvergue | ||||
| G1 | AC Milan | H | 0-0 | A | 2-0 | Odemwingie, Keita | |||||
| G1 | AEK Athina | H | 3-1 | Robail, Gygax, Makoun | A | 0-1 | |||||
| 08 | Manchester United FC | H | 0-1 | A | 0-1 | ||||||
| 09-10 | E3 | P3 | FK Sevojno | A | 2-0 | Vittek, Hazard | H | 2-0 | Cabaye, Túlio | ||
| P4 | KRC Genk | A | 2-1 | Dumont, Vittek | H | 4-2 | Túlio (2), Dumont, Hazard | ||||
| G1 | Valencia CF | H | 1-1 | Gervinho | A | 1-3 | Chedjou | ||||
| G1 | SK Slavia Praha | A | 5-1 | Suchý (o.g.), Frau, Gervinho (2), Souquet | H | 3-1 | Cabaye, Gervinho, Obraniak | ||||
| G1 | Genoa Cricket & FC | H | 3-0 | Obraniak, Vittek, Hazard | A | 2-3 | Frau, Gervinho | ||||
| 16 | Fenerbahçe SK İstanbul | H | 2-1 | Balmont, Frau | A | 1-1 | Rami | ||||
| 08 | Liverpool FC | H | 1-0 | Hazard | A | 0-3 | |||||
| 10-11 | E3 | P4 | FC Vaslui | A | 0-0 | H | 2-0 | Cabaye, Chedjou | |||
| G1 | Sporting CP Lisboa | H | 1-2 | Frau | A | 0-1 | |||||
| G1 | KAA Gent | A | 1-1 | Frau | H | 3-0 | Obraniak, Frau, Sow | ||||
| G1 | PFK Levski Sofia | H | 1-0 | Chedjou | A | 2-2 | Túlio, Ivanov (o.g.) | ||||
| 16 | PSV Eindhoven | H | 2-2 | Gueye, Túlio | A | 1-3 | Frau | ||||
| 11-12 | E1 | G1 | FK CSKA Moskva | H | 2-2 | Sow, Pedretti | A | 2-0 | Berezutsky (o.g.), Sow | ||
| G1 | Trabzonspor Kulübü | A | 1-1 | Sow | H | 0-0 | |||||
| G1 | FC Internazionale Milano | H | 0-1 | A | 1-2 | Túlio | |||||
| 12-13 | E1 | P4 | FC København | A | 0-1 | H | 2-0 | * | Digne, Túlio | ||
| G1 | FK BATE Barysaw | H | 1-3 | Chedjou | A | 2-0 | D.Sidibé, G.Bruno | ||||
| G1 | Valencia CF | A | 0-2 | H | 0-1 | ||||||
| G1 | FC Bayern München | H | 0-1 | A | 1-6 | Kalou | |||||
| 14-15 | E1 | P3 | Grasshopper-Club Zürich | A | 2-0 | Corchia, Ryan Mendes | H | 1-1 | Balmont | ||
| P4 | FC Porto | H | 0-1 | A | 0-2 | ||||||
| E3 | G1 | FK Krasnodar | H | 1-1 | S.Kjær | A | 1-1 | Roux | |||
| G1 | VfL Wolfsburg Fußball | A | 1-1 | Origi | H | 0-3 | |||||
| G1 | Everton FC Liverpool | H | 0-0 | A | 0-3 | ||||||
| 16-17 | E3 | P3 | Qәbәlә PFK | H | 1-1 | Ryan Mendes | A | 0-1 | |||
| 19-20 | E1 | G1 | AFC Ajax Amsterdam | A | 0-3 | H | 0-2 | ||||
| G1 | Chelsea FC London | H | 1-2 | Osimhen | A | 1-2 | Rémy | ||||
| G1 | Valencia CF | H | 1-1 | Ikoné | A | 1-4 | Osimhen | ||||
| 20-21 | E3 | GS | AC Sparta Praha | A | 4-1 | Yusuf Yazıcı (3), Ikoné | H | 2-1 | Burak Yılmaz (2) | ||
| GS | Celtic FC Glasgow | H | 2-2 | Mehmet Zeki Çelik, Ikoné | A | 2-3 | Inoké, Weah | ||||
| GS | AC Milan | A | 3-0 | Yusuf Yazıcı (3) | H | 1-1 | Bamba | ||||
| 16 | AFC Ajax Amsterdam | H | 1-2 | Weah | A | 1-2 | Yusuf Yazıcı | ||||
| 21-22 | E1 | GS | VfL Wolfsburg-Fußball | H | 0-0 | A | 3-1 | Burak Yılmaz, David, Angel Gomés | |||
| GS | FC Salzburg | A | 1-2 | Burak Yılmaz | H | 1-0 | |||||
| GS | Sevilla FC | H | 0-0 | A | 2-1 | David, Ikoné | |||||
| 08 | Chelsea FC London | A | 0-2 | H | 1-2 | Burak Yılmaz | |||||
| 22-23 | E4 | Q4 | HNK Rijeka | H | 2-1 | Zhegrova, Yoro | A | 1-1 | * | David | |
| GS | NK Olimpija Ljubljana | H | 2-0 | David, Yusuf Yazıcı | A | 2-0 | Cabella, Yusuf Yazıcı | ||||
| GS | KÍ Klaksvík | A | 0-0 | H | 3-0 | Yusuf Yazıcı, Angel Gomés, Zhegrova | |||||
| GS | ŠK Slovan Bratislava | H | 2-1 | Yusuf Yazıcı, Cabella | A | 1-1 | Angel Gomés | ||||
| 08 | SK Sturm Graz | A | 3-0 | David (2), Zhegrova | H | 1-1 | Tiago Santos | ||||
| 04 | Aston Villa FC Birmingham | A | 1-2 | Diakité | H | 2-1 | & | Yusuf Yazıcı, André | |||